Tsu'bo negation tank

Simple and Effective
How to play:

Tsu'bo's Boom-Chakas to poke waiting for enemy to over extend. Use right click to Stun/Root then decide to either dive onto target OR dive into the backline and pull aggro from the other 2 enemies.

Jump in with Tsu'bo's Ripper Blades to start brawling with enemy backline, focus on assassin's and mages. If they start trying to jump away, you can auto attack twice then animation cancel with dash. Slow down this combo by 0.5 seconds and with practice your dash charge will reset before you dash again, allowing you to infinitely auto attack twice and move.

Use Resilience Crown first when starting to get attacked, that will negate 70% damage for 3 seconds. If you feel you are not tanking enough damage then use the right click of Tsu'bo's Ripper Blades to negate another 50% damage from enemies for 3 seconds (stacks) (4 seconds if leveled to 3) OR I recommend waiting until the crown is done then use your ability. That would give 6-7 seconds of damage mitigation.

After both of those are on cooldown use Invulnerable Amulet to either stay on target and secure the kill, use it to drink down a Fortitude Shard to help heal up if you don't think you can get away alive at that time, or dash away, preferably around a corner, then heal up. Wait for cooldowns while you reposition then jump back in. Advanced level's of play would wait to use the Invulnerable Amulet until the last second in a close fight to bait an enemy to committing to the fight thinking they are going to win, instead of trying to disengage and run if you pop too early.

During this time, you should be able to fight a 1v2 while your teammates hopefully secure their 2v1 kill.